It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Hydroxychloroquine and l lysine Plaquenil painful muscle spasms The hallmark of hydroxychloroquine toxicity is bilateral pigmentary retinopathy. Patients with early retinal findings are often asymptomatic despite having subtle paracentral scotomas. Patients with early retinal findings are often asymptomatic despite having subtle paracentral scotomas. Dec 04, 2014 Hydroxychloroquine HCQ is an anti-malarial medication that has in recent times been utilized as treatment for a variety of autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, and other inflammatory and dermatologic conditions. The pattern of retinopathy caused by both HCQ and CQ is similar, but is much less common with HCQ. The earliest clinical changes in HCQ retinopathy are subtle changes at the macula, with pigmentary stippling and loss of the foveal reflex the typical light reflection seen on fundoscopy. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine maculopathy Hydroxychloroquine Uses, Dosage & Side Effects -, Hydroxychloroquine retinopathy A review of imaging What eye exam is needed for plaquenil Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARD. It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Hydroxychloroquine Side-effects, uses, time to work. Hydroxychloroquine-related retinal toxicity Rheumatology.. Chloroquine retinopathy - Wikipedia. To reduce the incidence of chloroquine and hydroxychloroquine toxicity, health care providers HCP's that prescribe these medications and those that screen for ocular toxicity have developed clear dosing and screening protocols that have reduced the risk of end-stage disease; bull's eye maculopathy and central vision loss Level I. Drug induced maculopathy Patterns of retinal toxicity. Chloroquine and Hydroxychloroquine. Chloroquine and its derivative, hydroxychloroquine sulfate. Phenothiazines. This is an antipsychotic drug used in schizophrenia & related psychoes. Tamoxifen. It’s a nonsteroidal estrogen antagonist used. Hydroxychloroquine is a prescription drug. It comes as an oral tablet. Hydroxychloroquine is available as the brand-name drug Plaquenil. It’s also available in a generic version.