Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. This medication is used to kill the malaria parasites living inside red blood cells. Hydroxychloroquine lupus nephritis Hydro chloroquine Combination of 1 mg/kg chloroquine with either 30 mg/kg or 60 mg/kg of goniothalamin decreased the parasitemia of P. yoelii infected mice more than 90% and prolong the survival up to 100% after. Chloroquine-susceptible strain of Plasmodium berghei ANKA, murine malaria parasite was a kind donation from Professor Peter Smith University of Cape Town, Division of Clinical Pharmacology, South Africa. The parasite was sub-cultured, harvested and stored in a Bio Ultra freezer Snijers Scientific, Tilburg, Netherlands at −80 °C until use. The combination therapy model of andrographis paniculata extract and chloroquine on plasmodium berghei infected mice Article PDF Available January 2015 with 72 Reads How we measure 'reads' Both drugs may be needed for a complete cure and to prevent the return of infection (relapse). In some cases, you may need to take a different medication (such as primaquine) to kill the malaria parasites living in other body tissues. Chloroquine treatment of berghei i.p Treatment of Plasmodium berghei Infection in Rats., Asiatic acid influences parasitaemia reduction and ameliorates malaria. What does chloroquine do in gelPlaquenil sjogren disease doesnt work Suitability of anti-erythrocyte Fab’2-bearing liposomes as vehicles for chloroquine in the treatment of chloroquine resistantPlasmodium berghei infections in mice has been examined. Free chloroquine or chloroquine encapsulated in antibody-free liposomes failed to show much effect on the resistant infections, but the same doses of this drug after being encapsulated in antibody-bearing. Chloroquine delivery to erythrocytes in Plasmodium berghei.. PDF THE COMBINATION THERAPY MODEL OF ANDROGRAPHIS.. Studying the effect of chloroquine on sporozoite-induced protection and.. Among the drugs used in rodent's malaria treatment, chloroquine was the most effective on P. berghei. No adverse effect of chloroquine was observed on the mice testes. Survival rate of mice was shown in Figure 2. Average life span was 15 days in the third group. Hepatic heme-oxygenase and heme levels were monitored during Plasmodium berghei infection and chloroquine treatment in Swiss albino mice. A progressive increase in heme-oxygenase and heme levels was noticed with the rise in parasitemia. Strains of Plasmodium berghei are readily made resistant to pyrimethamine this Bulletin, 1953, v. 50, 92 but less easily to chloroquine ibid. 1958, v. 55, 374, Cross-resistance to quinine has been described in a strain resistant to chloroquine ibid. 1965, v. 62, 82. Strains of P. berghei highly resistant to these 3 drugs have been selected from a sensitive parent strain, by treating.