This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Test for plaquenil retinopathy Chloroquine help with payment for prescriptions Plaquenil and wet macular degeneration How to treat plaquenil toxicity Primaquine is an N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N4 position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia. It has a role as an antimalarial. We would like to show you a description here but the site won’t allow us. The same reactive metabolites are believed to be responsible for oxidant hemolysis in patients with glucose-6-phosphate dehydrogenase G6PD deficiency. The present study was conducted in healthy volunteers to investigate the potential pharmacokinetic interactions between primaquine and chloroquine. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Primaquine chloroquine interaction Side Effects of Primaquine Phosphate Tablets, Warnings, Uses, Does plaquenil reduce painIs chloroquine-primaquine capitalizedHydroxychloroquine hair growthHydroxychloroquine and pres May 23, 2019 Along with its needed effects, primaquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking primaquine Incidence not known. Back, leg, or stomach pains; black, tarry stools Primaquine Side Effects Common, Severe, Long Term -. Pharmacokinetic Interactions between Primaquine and.. Primaquine - Wikipedia. Cautions. Since anemia, methemoglobinemia, and leukopenia may occur following administration of large doses of primaquine, do not exceed adult dosage of 1 tablet = 15 mg base daily for fourteen days; make routine blood examinations particularly blood cell counts and hemoglobin determinations during therapy; drug should be discontinued immediately. Safety data through day 29 are presented to avoid the potential confounding effects of retreatment with primaquine plus chloroquine in the event of patients having recurrence. Primaquine is used after other medications such as chloroquine have killed the malaria parasites living inside red blood cells. Primaquine then kills the malaria parasites living in other body tissues. This prevents the return of the infection. Both drugs are needed for a complete cure.