It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Chloroquine topical Plaquenil e nausea Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Lialda, which is a brand name for mesalamine, also reduces inflammation in the colon, however it does so in a very different way. Mesalamine interferes with production of a certain type of hormones, prostoglandins, as well as leukotrienes and other factors which tell the immune system to produce more inflammatory. Hydroxychloroquine is an investigational drug that is categorized as an immune modulator. 2 Immune modulators also called immunomodulators are substances that help to activate, boost, or restore normal immune function. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Is hydroxychloroquine an immune modulator Drugs acting on the immune system Pharmacology Education., What is the difference between immunosuppressants and. Plaquenil uses and side effects Chinese found an In Vitro activity of Plaquenil, and maybe in Vivo too but the live study is not yet published. A Professor in France got interested in. Hydroxychloroquine / Plaquenil and the Covid-19 / Coronavirus.. Hydroxychloroquine Clinical Trials, Side Effects AIDSinfo. ARTHRITIS TREATMENTS DMARDS AND OTHER IMMUNE MODULATORS 1.. Jun 18, 2015 Interestingly, as described for hydroxychloroquine, auranofin was shown to disrupt in various cell lines the TLR-4 signaling, which is activated by bacterial lipopolysaccharides and likely constitutes another source of immune hyperactivation. The most common condition where IRIS has been reported is tuberculosis TB. Various mechanisms have been proposed and studied to account for the immune regulatory role of hydroxychloroquine HCQ. A comparative list of treatment options for arthritis including DMARDS and other immune modulators.