Using plaquenil in end stage macular degeneration

Discussion in 'Canadian Ed Drugstore' started by blackwizard, 11-Mar-2020.

  1. Alex_vorontsov Well-Known Member

    Using plaquenil in end stage macular degeneration


    One class of medications can lead to more severe vision loss in people with the wet form of the disease, and another class of drugs may have a beneficial effect. Fortunately, very few prescription drugs have any known detrimental effects for people with AMD.

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    Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. The investigators think that there is a connection between the use of plaquenil and the prevention of Age related macular degeneration AMD. The investigators believe that the use of plaquenil makes bruch's membrane thicker, thereby preventing Chroidal Neovascularization CNV growth. Because the patient has previous macular pathology, should we make a recommendation to stop the Plaquenil? It’s an important question to address, because pre-existing macular pathology is a risk factor for the development of retinal toxicity according to the new screening recommendations.

    Doctors often put patients with certain potentially life-threatening cardiovascular conditions on this blood thinner. Warfarin (Coumadin®), which is an anticoagulant blood thinner, is one exception.

    Using plaquenil in end stage macular degeneration

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  5. Researchers suggest that one central point in both eyes indicates toxicity and one should have a low threshold with regards to any defects. 19 The misinterpreted visual field defect using the larger testing strategies could potentially delay the diagnosis of Plaquenil toxicity resulting in irreversible vision loss. Due to the possibility of.

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    I have been diagnosed with Limited Scleroderma. My choices are Methotrexate, Plaquenil or Sulfasalzine Azulfidine. I researched them and determined Plaquenil would be my last choice, although it was his first, because I already have lattice degeneration of the retina in both eyes and one of the potential side effects is retinal problems. What is Plaquenil or hydroxychloroquine? Hydroxychoroquine is an oral medication used for the treatment of rheumatologic conditions like lupus systemic lupus erythematosus – SLE, rheumatoid arthritis and other inflammatory conditions. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications.

     
  6. niklab Well-Known Member

    Malaria is associated with a reduction in the systemic clearance and apparent volume of distribution of the cinchona alkaloids; this reduction is proportional to the disease severity. Pharmacology of Chloroquine and Hydroxychloroquine. Pharmacokinetics of hydroxychloroquine and chloroquine. Mechanisms of action of hydroxychloroquine and chloroquine.
     
  7. mio_ Well-Known Member

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Hydroxychloroquine Side-effects, uses, time to work Hydroxychloroquine - American Osteopathic College of. Drug spotlight on hydroxychloroquine Lupus Foundation of.
     
  8. Dima798 New Member

    Chloroquine Effectively Inhibits Coronavirus Infection and Spread A report states that an old malaria drug known as Chloroquine effectively inhibits coronavirus infection and spread. In a three-page paper published in Cell Research, scientists at the Wuhan Institute of Virology’s State Key Laboratory of Virology wrote that both Chloroquine and the antiviral Remdesivir were, individually, “highly effective” at inhibiting replication of the novel.

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