Chloroquine resistance mechanism of action

Discussion in 'Canadian Pharmacy Online' started by doob, 06-Mar-2020.

  1. Serverex Guest

    Chloroquine resistance mechanism of action


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Apr 24, 2018 Learn about Chloroquine Mechanism of action and resistance in 2 minutes. Presenter Dr. Tanmay Mehta MD, DNB, PGDCTM Recently, an altered chloroquine-transporter protein CG2 of the parasite has been related to chloroquine resistance, but other mechanisms of resistance also appear to be involved. Research on the mechanism of chloroquine and how the parasite has acquired chloroquine resistance is still ongoing, as other mechanisms of resistance are likely. In this video, I will explain into one of the main antimalarial drug, chloroquine. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine resistance mechanism of action

    Chloroquine-Resistant Malaria The Journal of Infectious., Chloroquine - Wikipedia

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  3. Chloroquine acts by interfering with the sequestration of toxic heme ferriprotoporphyrin IX moieties produced when hemoglobin is digested by the intra-erythrocytic parasite to obtain a major.

    • Antimalarial Drugs Modes of Action snd Mechanisms of..
    • Antimalarial Drug Mechanism of Action What is Chloroquine?.
    • Mechanisms of drug action and resistance.

    Oct 01, 2018 Mechanism of Action Chloroquine, a 4-aminoquinoline, is an anti-protozoal agent. The precise mechanism by which Chloroquine exhibits activity is not known. Chloroquine, may exert its effect against Plasmodium species by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. Mechanism of Action Chloroquine, a 4-aminoquinoline, is an anti-protozoal agent. The precise mechanism by which chloroquine exhibits activity is not known. Chloroquine, may exert its effect. Learn about Chloroquine Mechanism of action and resistance in 2 minutes. Presenter Dr. Tanmay Mehta MD, DNB, PGDCTM

     
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