Please review the following URL and make sure that it is spelled correctly. Hi everyone, My Rheumatologist told me he has to take me off of Prednisone and wants to start me on another RX. My choices are Methotrexate, Plaquenil or Sulfasalzine (Azulfidine). Metformin versus hydroxychloroquin for tyle 2 diabetes Purifying chloroquine phospahte Is hydroxychloroquine the same as plaquenil Sulfasalazine oral tablet is a prescription medication that's used to treat rheumatoid arthritis, juvenile rheumatoid arthritis, and ulcerative colitis. It's available as generic drugs and as the. Methotrexate vs sulfasalazine. Follow. methotrexate and sulfasalazine. She suggested methotrexate as it seems to be the best. unfortunately I had to take other meds too like Plaquenil and later Cimzia injections to reduce the inflammation and the combination led to liver problems and I am now off MTX and in more pain but hoping that. Sulfasalazine is a type of drug known as a disease-modifying anti-rheumatic drug DMARDmay be used on its own or with other drugs. Sulfasalazine changes the way your condition affects you, and reduces inflammation, pain and swelling in your joints. So, I guess my question is, between the two remaining choices, which would you all recommend? I researched them and determined Plaquenil would be my last choice, although it was his first, because I already have lattice degeneration of the retina in both eyes and one of the potential side effects is retinal problems. Sulfasalazine vs hydroxychloroquine Treatment of rheumatoid arthritis with methotrexate and., Methotrexate vs sulfasalazine. Rheumatoid Arthritis. Sam's club pharmacy hydrochloride hydroxychloroquinePlaquenil sarcoidosis treatmentG6pd and hydroxychloroquine Background/Purpose The combination of methotrexate MTX, sulfasalazine SSZ and hydroxychloroquine HCQ triple therapy is a highly effective and well-tolerated treatment in rheumatoid arthritis RA. While MTX is the cornerstone of most successful combination therapies, not all patients are candidates for, or tolerate, MTX. Leflunomide, Sulfasalazine and Hydroxychloroquine for.. Sulfasalazine Side-effects, uses, time to work. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Sulfasalazine SSZ, sold under the trade name Azulfidine among others, is a medication used to treat rheumatoid arthritis, ulcerative colitis, and Crohn's disease. It is considered by some to be a first line treatment in rheumatoid arthritis. It is taken by mouth. If the plaquenil is helping and they say you need it, I'd take it - the side effects will go away. I've not had experience with sulfasalazine - but from what I've read, the side effects of that med are about the same as those of plaquenil. BTW - sulfasalazine is an anti-inflammatory. Summary Drug interactions are reported among people who take Sulfasalazine and Plaquenil together. This study is created by eHealthMe based on reports of 7,132 people who take Sulfasalazine and Plaquenil from Food and Drug Administration FDA, and is updated regularly.