Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine overdose amount Can i take plaquenil and simvastatis So after three weeks of taking Plaquenil hydroxychloroquine I developed a rash and had to stop. Now I'm really worried since Plaquenil is supposed to be the 'life insurance' drug of lupus, people have less flares on it, live longer, etc. Does this mean I have to be on steroids, and/or stronger drugs like Imuran and Cellcept, forever? What is Plaquenil? Plaquenil is a drug used in the acute treatment of malaria. It is also used in the long –term treatment of rheumatoid arthritis and lupus erythematosus. Its generic name is hydroxychloroquine sulfate. Chloroquine has been replaced with hydroxychloroquine as it has less side effects. Eye Exam Before Starting Treatment That's a real common side effect of Lupus is unexplained rashes. If you've ever had an allergic reaction to a drug then this is the type of reaction you'd have if you were allergic to the Plaquenil; and they'd stay until the Plaquenil was out of your system. If they're coming and going more than likely it isn't the Plaquenil. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Allergic reaction when changed from hydroxychloroquine to plaquenil Plaquenil Hydroxychloroquine Side Effects and Adverse., Plaquenil Hydroxychloroquine Side Effects and Adverse Reactions Hydroxychloroquine methemoglobinemiaPlaquenil vs humiraCan plaquenil cause tiredness Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Hydroxychloroquine Side Effects Common, Severe, Long Term.. Plaqunil rash -. Allergic reaction to plaquenil DailyStrength. Allergic reaction to Plaquenil. Discussion in 'Medications' started by SickANDexhausted, Mar 25, 2015. SickANDexhausted Junior Member. I was just prescribed Plauqenil and was given Hydroxycloroquine Zydus. Less than two weeks in, I had an extremely bad allergic reaction. It started out with these ugly, itchy red hives on my left arm. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate. the patient should be closely observed given that retinal changes and visual disturbances may progress even after cessation of therapy. Cardiac Effects. Dermatologic reactions to PLAQUENIL may occur and, therefore, Increased cutaneous reactions to hydroxychloroquine Plaquenil possibly associated with formulation change Comment on the letter by Alarcón. M. Salido MD, PhD. Hospital Clinico San Carlos, Madrid, Spain. Rayne Institute, St. Thomas' Hospital, London, UK. Search for more papers by this author.