These interactions are explained in the Proton Pump Inhibitors article, which is part of the extensive Drug Interactions section of our website (where you can look up interaction for other drugs you may be taking). Be sure to also read about magnesium depletion which can occur with these drugs in the Magnesium Supplements Review. Plaquenil hydroxychloroquine sulfate Lysosomal acidification chloroquine Allergic reaction from generic to plaquenil Chloroquine and osmotic lysis If taken in combination with these drugs, it will actually increase your body’s production of stomach acid. This can cause nausea, bloating and stomach pain and can also damage your esophagus. Drugs that reduce stomach acid include Cimetidine Tagamet, Famotidine Pepcid, Ranitidine Zantac and Omeprazole. Antimalarial Drugs. If your plans include travel to southern Africa or another part of the world where malaria is common, you might need medicine to protect yourself against the mosquito-borne disease. But be aware. If you have psoriasis, chloroquine Aralen and hydroxychloroquine Plaquenil can cause problems. Summary Drug interactions are reported among people who take Omeprazole and Hydroxychloroquine sulfate together. This study is created by eHealthMe based on reports of 1,041 people who take Omeprazole and Hydroxychloroquine sulfate from Food and Drug Administration FDA, and is updated regularly. Also see the Encyclopedia article about Gastroesophageal Reflux Disease (GERD) for other proposed treatments for this condition, including deglycyrrhizinated licorice, marshmallow, slippery elm and others, as well as our CL Answer about supplements for indigestion and heartburn. I have GI problems and wonder if I should avoid turmeric and curcumin? And, if you take a calcium supplement, read in the Calcium Supplements Review how certain forms of calcium may be preferable if you are taking these drugs. Omeprazole and plaquenil Drugs That May Interact with CBD Oil Learn More CBD., Drugs & Medications That Can Trigger Psoriasis Flare-Ups Hydroxychloroquine and pregnancyPlaquenil not working what nextPlaquenil liver failureWhat does plaquenil do for you Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. Plaquenil Oral Interactions with Other Medication. Omeprazole and Hydroxychloroquine sulfate drug interactions.. Is it safe to take Linzess 145mcg & Omeprazole 40mg.. Plaquenil. A total of 324 drugs are known to interact with Plaquenil. Plaquenil is a member of the following drug classes antimalarial quinolines, antirheumatics. Compare Hydroxychloroquine vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Hydroxychloroquine rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Aug 14, 2017 Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term.