In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Plaquenil and hair dye Hydroxychloroquine sulfate and weight loss Can you take hydroxychloroquine with prednisone How long does plaquenil take to work Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Download PDF. Drug-induced ocular side effects are back in the spotlight, thanks to the Academy’s revision of its recommendations on screening for retinal toxicity from chloroquine and its analogue hydroxychloroquine Plaquenil. 1 There are hundreds of drugs with potential retinal toxicity—so many that the National Registry of Drug-Induced Ocular Side Effects doesn’t stratify them by. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. How does hydroxychloroquine effect the eyes Eye screening for patients taking hydroxychloroquine., Hydroxychloroquine Side Effects Common, Severe, Long Term. Chloroquine or proguanilOf dropout in rheumatoid arthritis treatment with hydroxychloroquineIs plaquenil safe long term Inability to move the eyes increased blinking or spasms of the eyelid joint or muscle pain large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, and sex organs loss of hearing lower back or side pain noisy breathing painful or difficult urination red irritated eyes Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Rx Side Effects New Plaquenil Guidelines and More.. Hydroxychloroquine-Induced Retinal Toxicity - American.. There is a small risk that hydroxychloroquine can damage your retina part of the eye, and this increases with long-term use and higher dosage. Your doctor will advise you on a safe dose to take according to your weight, and you will need to have regular monitoring of your eyes. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Rare but potentially serious eye toxicity can occur. This toxicity affects a part of the eye called the retina and can lead to color blindness and even loss of vision. An. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble.