Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. What are plaquenil deposits Aralen lupus The Dangers of Going Cold Turkey Individuals can really shock their systems if they try to stop taking Xanax altogether without weaning off it. When a person is abusing this drug, the body becomes accustomed to the effects it causes, and without the drug, the body doesn’t know how to respond. Hi honey, YES.stopping plaquenil for a couple of days can cause symptoms to arise or get worse.needs to be taken exactly as prescribed. Twice a day, every day. Missing one dose wont make a major difference but skipping more then one, or days absolutely can. With the condition your in already by the sounds of it I wouldnt mess with it. why dont you just kinda fake it? the damage wouldnt be worth the cash. personally all I take is minocycline but if I was in your shoes I wouldnt stop if it provided a certain level of releif. and yes plaquenil does lose its affectiveness if you stop taking it. my moms cousin took it for years as it gave him the. Did you take yourself off Plaquenil, or did your doctor tell you to go off it? Plus I will be honest the whole eye site thing even though rare has always freaked me out. I went off of it to see if I can manage not being on it as my lupus isnt as severe as other cases but already I am feeling very fatigued and my legs feel heavy if that makes sense. I can discuss alternatives with my DR at my next appt but my DR feels as though the plaq is the best bet for my level of illness. If so are you just dealing with Lupus symptoms or did you take another med? I'm on Plaquenil, and after the first week's GI upset, I have had no problems with it. What could happen if you cold turkey plaquenil Cold Turkey’ Alcohol Withdrawal Can Cause Serious Health., Stopping plaquenil. DailyStrength Plaquenil side effects gum soresPlaquenil myositisTums and plaquenilIs hydroxychloroquine a blood thinnerCoupons for generic plaquenil If you are taking hydroxychloroquine for symptoms of rheumatoid arthritis, your symptoms should improve within 6 months. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you. Hydroxychloroquine MedlinePlus Drug Information. Plaquenil cold turkey - side effects? - Road Back Foundation. What is the correct way to discontinue use of plaquenil?. I have gone off Plaquenil cold turkey more times than I can remember. Every time I go on an antibiotic I have to stop the plaquenil as these 2 drugs together give so many CNS symptoms in the form of agitation, depression etc. I will have increase in my pain and aches and other little reminders that I need to be back on the drug. I have been reading up on stress and what that can cause and do to a person. My body feels so much better, what do you make of this? Thank you, Loretta. Answer. There is no problem with stopping methotrexate abruptly, with the exception that you might flare if you indeed have active ongoing RA. Talk to your rheumatologist You may report side effects to Health Canada at 1-866-234-2345. PRECAUTIONS Before taking hydroxychloroquine, tell your doctor or pharmacist if you are allergic to it; or to other aminoquinolines e.g. chloroquine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.