Today’s post discusses five drugs used to prevent malaria. Some of these are known causes of sensorineural hearing loss which may or may not be reversible; others produce auditory/vestibular symptoms such as tinnitus and dizziness. Adverse effects of hydroxychloroquine Can hydroxychloroquine cause weight gain Not only will it turn you yellow, it can lead to psychological effects depression and psychosis, seizures, permanent tinnitus and balance problems, and more. Other newer antimalarials such as mefloquine Lariam have the same problems. And so does chloroquine, at right. Before the administration of chloroquine, the patient had only a mild skin erythema in the irradiated area, which was consistent with the radiotherapy dose she had received. On day 3 of chloroquine therapy, she developed localized brisk bullous eruptions in the irradiated area, which developed into a patch of fulminant moist desquamation. Drugs that may cause tinnitus include very large doses of aspirin, such as more than 12 doses daily for a prolonged period. loop diuretic medications, such as bumetanide. antimalarial drugs, such as chloroquine. certain antibiotics, such as erythromycin and gentamicin. certain anti-cancer drugs, such as vincristine. But only 6% of those who contracted malaria in 2011 reported that they had followed CDC guidelines correctly. Mosquito avoidance is at the top of the list for preventing malaria. For travelers, there are five drug options which form the “chemoprophylactic” regimen recommended by the CDC for regions in which malaria is endemic: mefloquine, doxycycline, atovaquone/proguanil, chloroquine, primaquine. Chloroquine tinnitus Aralen chloroquine Malaria Drug Side Effects & Dosage, Chloroquine Side Effects Common, Severe, Long Term. Plaquenil dosage for sjogrens Chloroquine. In addition to its use as an antimalarial drug, chloroquine and hydroxychloroquine is used in the treatment of rheumatoid arthritis and connective tissue disease. Mechanisms of toxicity. Chloroquine causes cardiac sodium channel blockade, leading to slowing of atrioventricular conduction. Quinine and chloroquine - ScienceDirect. Tinnitus Causes, Diagnosis & Treatments. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. It is taken by mouth. Common side effects include muscle problems, loss of appetite, diarrhea, and skin rash. Serious Whether the sound is perceived in the left ear, right ear, or both ears, your tinnitus may be due to exposure to loud noise. jaw, or TMJ, conditions, cardiovascular disease. earwax buildup. hearing loss. certain medications. head or neck injuries. Antimalarial agents Quinine and chloroquine Aralen — Antimicrobial agents Aminoglycosides Tinnitus usually is an initial sign of ototoxicity, often with rapid progression to hearing loss; hearing.