In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Plaquenil for seronegative arthropathy Plaquenil combination therapy Immunodeficiency disorders is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take medication Humira, and have Mixed connective tissue disease. Plaquenil is a drug used to treat Rheumatoid Arthritis and Systemic Lupus Erythematosis. It is a very good drug and gives many patients significant relief from their symptoms. Plaquenil related eye complications are not common. Plaquenil can produce pigment changes in the macula of the retina. Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, ringing in your ears, mood changes, nervousness, irritability, skin rash, itching, or; hair loss. Tell your doctor if you experience serious side effects of Plaquenil including. muscle weakness, twitching, As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Is plaquenil dangerous Plaquenil Side Effects on Your Eyes and Vision, Conditions Plaquenil-related Eye Problems Eugene Eye Care Hydroxychloroquine 200 mg does it have steroids in itHydroxychloroquine eye problemsHydroxychloroquine tremorChloroquine phosphate user reviews Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. The Risk of Retinal Toxicity with Plaquenil. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil and Sulfa Allergies" Lupus Community - Support.. Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil may cause problems with the eyesight of some people. Make sure you know how you react to Plaquenil before you drive a car, operate machinery, or do anything else that could be dangerous with blurred vision. Side Effects. Tell your doctor or pharmacist as soon as possible if you do not feel well while taking Plaquenil. Plaquenil can be dangerous to children, who are particularly sensitive to the drug. Kids shouldn't take Plaquenil as a long-term treatment. Overdose can be fatal in children.