One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Chloroquine autophagy inducer Chloroquine er derived vaculation Hydroxychloroquine And Chloroquine Screening 2016 AAO Recommendations The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. The 2016 American Academy of Ophthalmology AAO Recommendations for Screening for Hydroxychloroquine and Chloroquine Retinopathy recommended a maximum daily HCQ use of 5.0 mg/kg real weight. The AAO also recommends a baseline fundus examination and annual screening after 5 years for patients without major risk factors. AAO revised guidelines. The AAO published dosing and screening recommendations for chloroquine and hydroxychloroquine in 2016, revising previous recommendations published in 2011. The current maximum daily HCQ dose recommended by the AAO is 5 mg/kg of real weight. The 2011 guidelines suggested a maximum dose of 6.5 mg/kg of ideal weight. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Aao guidelines for plaquenil Plaquenil Guidelines Point Out New Risks, New Presentation., The Great Debate at ACR 2018 Hydroxychloroquine Dosing for. Plaquenil synthesistChloroquine basePlaquenil capsule Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Despite Plaquenil dosing recommendations, retinal toxicity.. Hydroxychloroquine Professional Patient Advice -. Jun 13, 2019 Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision. AAO Screening Guidelines for Plaquenil by S P Check out my recent review/summary of the American Academy of Ophthalmology’s statement on the Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy 2016 Revision from the Ophthalmology Journal 2016;186-1394. New American Academy of Ophthalmology recommendations on screening for hydroxychloroquine retinopathy. To the Editor Chloroquine CQ and hydroxychloroquine HCQ are used widely in the treatment of rheumatic disease, and they have the potential to cause serious retinal toxicity when high doses have been taken over a long period of time.