It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil and tingling hands Can plaquenil and metoprolol tartrate Zentiva hydroxychloroquine Skin Hyperpigmentation with Hydroxychloroquine. Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, pseudopelade and discoid lupus. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. However, following an identical dose of. Aug 14, 2013 Hyperpigmentation was absent from her oral mucosa and nails. Fig. 1 Diffuse black hyperpigmentation of the forehead, face, neck, and v-area of the upper central chest of a woman with systemic lupus erythematosus who has been receiving hydroxychloroquine for more than 30 years. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil and oral pigmentation Drug spotlight on hydroxychloroquine Lupus Foundation of America, Hydroxychloroquine DermNet NZ Chloroquine skin pigmentationPlaquenil and itchy eyesApo hydroxychloroquineCan hydroxychloroquine cause hair lossWhat does plaquenil do for lupus patients Not for administration with other drugs that have potential to prolong QT interval; hydroxychloroquine prolongs QT interval; ventricular arrhythmias and torsades de pointes reported in patients taking hydroxychloroquine Skeletal muscle myopathy or neuropathy leading to progressive weakness and atrophy of proximal muscle groups. Plaquenil hydroxychloroquine sulfate dosing, indications.. Hydroxychloroquine-Associated Hyperpigmentation Mimicking.. Common and Rare Side Effects for Plaquenil Oral. Consumer information about the medication HYDROXYCHLOROQUINE - ORAL Plaquenil, includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug HYDROXYCHLOROQUINE - ORAL. Potential side effects of anti-malarial drugs include Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish tone. Dry skin. Loss of appetite. Abdominal bloating. Upset stomach. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth.