Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine copay assistance Why plaquenil is good for lupus Plaquenil 40 mg Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs. Erectile dysfunction drugs cause a range of side effects that are common, dosage-dependent and, thus far, fully reversible. They include changes in color and light perception, blurred vision, conjunctival hyperemia, ocular pain and photophobia. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Side effects plaquenil weight gain Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Hydroxychloroquine dry eyesSymptoms of allergic reaction to plaquenilDoes plaquenil help sjogren's syndromePlaquenil tablet uses The plaquenil has caused a weight gain of about 20-25 pounds for me. Since I was diagnosed with MCTD a year ago, Plaquenil has been the only medication besides eye supplements, thyroid meds - been stable for years, and most recently Evoxac that I have been given. Plaquenil & Weight Gain/Loss -. Rx Side Effects New Plaquenil Guidelines and More.. Common and Rare Side Effects for Plaquenil Oral. Weight increased is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Actemra, and have Pain. This study is created by eHealthMe based on reports of 57,706 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. I started Plaquenil in Feb. I'm anti meds but the time came to try improve quality of my life. The side effects in the 1st week were amplified fatigue & nausea for a good month. I kept taking them & now I don't have any side effects. My energy much better, no more daytime napping needed optition side the retina toxification is very rare. These side effects include high blood pressure, high blood sugar, weight gain, mood swings, loss of bone and eye disease." Dr. Lee also says that she doesn't usually recommend steroid shots.