Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Non aqueous titration of chloroquine Does plaquenil cause bile malabsorption Plaquenil behcet's Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. This study evaluates the efficacy of the combination of methotrexate and hydroxychloroquine against leflunomide, a new DMARD as initial therapy in severe active rheumatoid arthritis. Hydroxychloroquine is known to increase the potency of methotrexate as well as increase its safety profile and reduce the dose. Learn about drug interactions between hydroxychloroquine oral and methotrexate sodium oral and use the RxList drug interaction checker to check drug combinations. Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. Combination of plaquenil and methotrexate Combination therapy with methotrexate and hydroxychloroquine., Evaluation of efficacy of combination of methotrexate and. Plaquenil and skin issuesPlaquenil and prednisone during pregnancyNovo-chloroquine 250 mg effets secondaires Combined use of methotrexate with gold, penicillamine, hydroxychloroquine, sulfasalazine, or cytotoxic agents, has not been studied and may increase the incidence of adverse effects. Rest and physiotherapy as indicated should be continued. Methotrexate is available under the following different brand names Trexall, Otrexup, and Rasuvo. Methotrexate Trexall Side Effects, Dosages, Treatment.. Hydroxychloroquine oral and methotrexate sodium oral Drug.. The Combination of Leflunomide Arava and Methotrexate is.. Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications results of a two-year, randomized, double-blind, placebo-controlled trial, Apr 21, 2016 Objective To compare methotrexate based disease modifying antirheumatic drug DMARD treatments for rheumatoid arthritis in patients naive to or with an inadequate response to methotrexate. Design Systematic review and Bayesian random effects network meta-analysis of trials assessing methotrexate used alone or in combination with other conventional synthetic DMARDs, biologic drugs, or. If patients did not go into remission after four months, they were randomized either to a combination of multiple DMARDS and low-dose prednisone arm 1 or to adalimumab ADA and methotrexate arm 2. Arm 1 involved 25 mg/wk MTX, 400 mg/day hydroxychloroquine, 2000mg/day sulphasalazine, and 7.5 mg/day of prednisone.