I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Hydroxychloroquine teaching Chloroquine in lupus Plasmodium falciparum resistance to chloroquine What helps nausea from plaquenil I have been on plaquenil for 8 months and have lost 60 pounds from it this is a good thing also the fatigue is completely gone as is the morning stiffness. Plaq did not do enough to end my flare and get me off pred so doc convinced me to add MTX. She tried to take me off the plaq at my last appointment and I would NOT let her. Coming off Hydroxychloroquine. Staycalmandcarryon. If all goes well then I plan to come off HCQ completely in 4-6 months time. Rheumy says there is a risk RA could. Hydroxychloroquine Plaquenil is a very useful drug to treat Rheumatoid Arthritis and Lupus but it can have some significant visual side effects unless properly dosed and monitored. any of these changes as early as possible is because in many instances the changes are not reversible even if you come off the medication. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Coming off hydroxychloroquine Let me tell you what weaning down from Plaquenil is like., Coming off Hydroxychloroquine I went to see my rheumy. - NRAS Hydroxychloroquine sulfate tPlaquenil rash skinAre there withdrawal symptoms from plaquenilThe best way to taper off plaquenilChloroquine sensitive areas With the Plaquenil I don't think you will find much relief in such a short time on it & at half of a workable dose. I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. Hydroxychloroquine plaquenil withdrawl? - LUPUS UK. What can Hydroxychloroquine Plaquenil do to my eyes?. Prednisone Tapering Schedule to Reduce Withdrawal. I was only on it a month. I'm still coming out in it. It's not a rash really it looks like burns. My skin is peeling and even this morning some new patches have came up I wish someone could tell me how long this wretched drug will take to get out of my system. all together i have been off work five weeks so far. For patients taking hydroxychloroquine to prevent malaria Your doctor may want you to start taking this medicine 1 to 2 weeks before you travel to an area where there is a chance of getting malaria. This will help you to see how you react to the medicine. You can also put off joint damage, and in some cases, you can do more than just slow it down. Being able to stop joint damage can lessen pain and mean a better quality of life. Hydroxychloroquine is one of the medications that can be a valuable part of your treatment plan.