Plaquenil is less toxic than chloroquine; however, long-term use of either drug can result in macular toxicity, leading to devastating irreversible vision loss. The mechanism of this toxicity is not clearly understood, though it is believed that the drug molecule binds to melanin in the retinal pigment epithelium (RPE). Plaquenil and mobic Alternative for plaquenil Phototherapy and plaquenil combination Visual fields in a chloroquine treatment María del Carmen García-Domene,1,2 María Amparo Díez-Ajenjo,1,3 María Dolores de Fez,4 María José Luque2 1Fisabio Oftalmología Médica, València, 2Departament d'Òptica, Facultat de Física, Universitat de València, Burjassot, 3Clínica Optométrica Fundación Lluís Alcanyís, Valencia. Oct 01, 2018 Use of Chloroquine phosphate tablets for indications other than acute malaria is contraindicated in the presence of retinal or visual field changes of any etiology. Use of Chloroquine phosphate tablets is contraindicated in patients with known hypersensitivity to 4-aminoquinoline compounds. Warnings. Chloroquine-Resistant Malaria Purpose In this study, we describe contrast sensitivity losses in the visual field of a patient affected by chloroquine toxicity, measured with stimuli favoring different visual mechanisms. We have compared these results with those of other, usual clinical tests. Binding of the drug to melanin in the RPE contributes to, or prolongs, its toxic effects. This leads to disruption and damage to the photoreceptors and outer nuclear and plexiform layer, sparing the foveal center and resulting in the “bull’s eye” appearance in the late stage of the disease. Visual fields in chloroquine Visual Fields and Plaquenil Medical Billing and Coding., Chloroquine - FDA prescribing information, side effects and uses Plaquenil and pregnancy testHydroxychloroquine discontinued side effectsBuy chloroquinePlaquenil brand vs generic Mar 04, 2014 Visual fields in a chloroquine treatment María del Carmen García-Domene,1,2 María Amparo Díez-Ajenjo,1,3 María Dolores de Fez,4 María José Luque2 1Fisabio Oftalmología Médica, València, 2Departament d'Òptica, Facultat de Física, Universitat de València, Burjassot, 3Clínica Optométrica Fundación Lluís Alcanyís, Valencia. Full text Visual fields in a chloroquine treatment OPTO. Visual fields in a chloroquine treatment - CORE. Visual Field Test Learn How the Procedure Is Performed. Figure 1 shows the bilateral visual fields 10-2 pattern deviation plots and horizontal SD-OCT cross-sections from 5 of these patients cases 1–5. For all 11 patients, the fields were basically symmetric in showing a parafoveal ring scotoma, and there was no obvious SD-OCT damage in either eye. To quantify the variability of scotomas detected by 10–2 visual field VF testing with a red target in patients taking hydroxychloroquine without and with retinopathy. Retrospective review of clinical charts and VFs. Twenty-four patients taking. Visual fields may be determined by several methods including a tangent screen, Goldmann perimeter, and computerized automated perimeters. Visual field examinations may be indicated in the diagnosis and monitoring visual field loss due to blepharoptosis or to disease involving the cornea, lens, retina, optic nerve, and intracranial visual pathway.