I remember the crushing fatigue and hope that I never have to feel that way again. I was on Plaquenil for over a year with my Limited Systemic Sclerosis and didn't notice any effect, scleroderma still progressing. :( Next week I am going to consult with my scleroderma doc what next. It's generally prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. I remained on that dosage for the first five years. You have to have you eyes checked on a very regular basis as it can cause visual changes and difficulty. Plaquenil to treat mouth disease Can plaquenil cause insomnia Hydroxychloroquine and l lysine Hydroxychloroquine antiviral After that I was dropped to 200 mg two times a day. I'm now taking 200 mg. once a day as a therapitic dose. You have to have you eyes checked on a very regular basis as it can cause visual changes and difficulty. It's been a long time since I began taking it, but I don't remember any increase in energy. Plaquenil hydroxychloroquine is commonly used to help keep mild lupus-related problems, such as skin and joint disease, under control. This drug is also effective at preventing lupus flares. To soon,my rheumatolgist started me on 200 mg for 4 month's reviewed how getting on had made change with fatigue so added 2 pill to make 400mg reviewed again in another 4 month'improvement only mild side effect of headache first 2 weeks. told take 1 morning after food 1 evening after food a 12 hour gap between doses. But it had an almost immediate effect for me with respect to fatigue, which I attribute to it's effect on vitamin D regulation (or dysregulation in my case). There have been times when I've stopped taking it over the years and have noticed no change in my fatigue or pain levels. The swelling/tendonitis in my fingers & toes stopped progressing after about 3 months, but 9 months later, they are still somewhat stiff and swollen, so it's difficult to know what would have happened without it. After that I was dropped to 200 mg two times a day. It's been a long time since I began taking it, but I don't remember any increase in energy. 200 mg of plaquenil how long to work Plaquenil Oral Uses, Side Effects, Interactions., How is plaquenil hydroxychloroquine used to treat lupus? Scholarly articles plaquenil gad65Hydroxychloroquine for lupus user reviews To 5’ 6 1/2” - up to 300 mg Plaquenil daily; 5’ or shorter - up to 200 mg Plaquenil daily; Women with lupus who are AT OR BELOW their ideal body weight should go by these dosing rules 135 lbs. or more, any height - up to 400 mg Plaquenil daily; 102 lbs. to 134 lbs. - up to 300 mg Plaquenil daily Protecting your eyesight when taking Plaquenil Lupus Foundation of.. How long did hydroxychloroquine take to work. - HealthUnlocked. Taking Plaquenil for Rheumatoid Arthritis. Strength 200 mg; Brand Plaquenil. Form oral tablet; Strength 200 mg; Dosage for malaria. Adult dosage ages 18 years and older Acute attack Typical starting dose is 800 mg. I take methotrexate injections weekly along with antibotic thereaphy of 200 mg of minocycline. Last week my doc added plaquenil to the mix. I have a pharmacist friend that says it can take up to a year to work, but once its kicks in it can be really good. Generally, hydroxychloroquine is given in 200 mg or 400 mg doses, once per day. Higher doses can sometimes be used, but only in adults and not for all cases. Some people tolerate this medication much better than other people, so it is important that individuals who are considering taking hydroxychloroquine talk with their doctor about the lowest necessary dose to reduce or eliminate their symptoms.