Please review the following URL and make sure that it is spelled correctly. Plaquenil is the brand name for the prescription drug hydroxychloroquine. Mechanism of action hydroxychloroquine Chloroquine and prostate cancer Does hydroxychloroquine lower your immune system Hydroxychloroquine and acetaminophen Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. but it may be used for long-term treatment of. Several risk factors may increase the likelihood of retinal toxicity from Plaquenil such as, age of greater than 60 years, daily dose more than 6.5 mg/kg; use of the drug more than 5 years, obesity, preexisting retinal disease and, renal or liver failure. Long term current use of etanercept; Long term current use of etanercept enbrel Long term current use of felbamate felbatol Long term current use of filgrastim neupogen Long term current use of golimumab simponi Long term current use of humira; Long term current use of hydroxychloroquine plaquenil Long term current use of infliximab. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Long term use of plaquenil Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis., The Risk of Retinal Toxicity with Plaquenil Treatment of chloroquine resistant malaria in pregnancy Safety of Long term use of Hydroxychloroquine Therapy Further Verified for People with Lupus. Hydroxychloroquine Plaquenil® was approved by the Food and Drug Administration for symptoms of lupus. The greatest concern people with lupus have when taking hydroxychloroquine is related to vision and an increase in risk for retinal damage. Safety of Long term use of Hydroxychloroquine Therapy.. ICD-10-CM Diagnosis Code Z79.899 Other long term.. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Plaquenil is the most common antimalarial drug given to treat lupus, and most physicians with experience in lupus agree that antimalarial treatments should be used long-term, year-after-year in all patients who can tolerate them. Learn why treatments that were developed for malaria are now used for lupus. Read the study Note that chloroquine is not used frequently in the United States and has been replaced by the use of hydroxychloroquine because the latter has fewer side effects. The Plaquenil Problem “Plaquenil toxicity is very distinctive,” said Michael F. Marmor, MD, professor of ophthalmology at Stanford University. Dr.