One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine allergic reaction What to use when plaquenil and sulfasalazine doesn't work Can hydroxychloroquine cause low white blood cell count Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Plaquenil can produce pigment changes in the macula of the retina. The retina is the part of the back of the eye that you see with. The macula is the central part of the retina responsible for central fine vision. With Plaquenil related toxicity, the pigment in the macula can change and alter vision by producing blurring and distortion of objects. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Whats the dosage that causes plaquenil toxicity Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil blistersCan hydroxychloroquine cause a false positive for pregnancyHow much is plaquenil without insurancePlaquenil short term side effects I normally post on the arthritis board, and due to toxicity of the Plaquenil after 2 years, I have had to discontinue it, since I failed the visual field testing. Although I take Enbrel, and MTX, neither one work as well as the Plaquenil and the fatigue and joint pain have returned full force. Discontinued Plaquenil.other options?. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Taking Plaquenil for Rheumatoid Arthritis. Jan 03, 2020 Weight based dosage in adults and pediatric patients 13 mg/kg 10 mg/kg base, not to exceed 800 mg 620 mg base followed by 6.5 mg/kg 5 mg/kg base, not to exceed 400 mg 310 mg base, at 6 hours, 24 hours and 48 hours after the initial dose. PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. What is Plaquenil Toxicity? The toxicity resulting from the intake of Plaquenil is due to its affinity for melanin-containing structures in the body. With prolonged usage, metabolites in the drug accumulate in the retina. The drug remains in these parts even if the patients stopped taking the drugs.