Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Chloroquine resistance in p vivax Plaquenil dosage forms Plaquenil side effects sweating Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye; Although rare, Plaquenil can cause significant toxicity to the eye with prolonged use. Also, Plaquenil may have various systemic side effects that are not related to the eyes. These too are rare and include nerve weakness, hallucinations, psoriasis and changes in hair color. The eye complications are the most serious and worrisome. Plaquenil and Your Eyes In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. The condition sometimes resembles a target, or bulls-eye ring, on the retina surrounding the macula. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Eye complications from plaquenil What Eye Problems and Conditions Are Associated With Lupus?, PLAQUENIL hydroxychloroquine and the Eye Westford Can plaquenil affect your thyroidHydroxychloroquine and tattoosChloroquine treatment for cellsRetail cost of plaquenil Sep 13, 2019 yellow eyes or skin; Symptoms of overdose. Drowsiness; dry mouth; increased thirst; loss of appetite; mood changes; no pulse or blood pressure; numbness or tingling in the hands, feet, or lips; unconsciousness; Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Side Effects on Your Eyes and Vision. Am I experiencing eye problems from Plaquenil? lupus. The effects lupus may have in and around the eyes include changes in the skin around the eyelids, dry eyes, inflammation of the white outer layer of the eyeball, blood vessel changes in the retina, and damage to nerves controlling eye movement and affecting vision. Jun 13, 2019 Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision. Some of the medications used to treat rheumatoid arthritis, such as prednisone a corticosteroid and Plaquenil hydroxychloroquine, can actually trigger eye problems. “Plaquenil, on rare.