Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Normal dosage for plaquenil Does plaquenil have lifetime effects Plaquenil is also used in some circumstances to control arthritis and may result in a lichenoid reaction or rash on the inside of the mouth. Immunosuppressive medications such as cyclophosphamide or methotrexate may result in opportunistic bacterial infection which could compromise periodontaly involved teeth or dental implants. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Evidence for this comes from a randomized clinical trial in which patients with rheumatoid arthritis RA were assigned to either continue on methotrexate MTX or suspend taking it for 2 weeks before and 2 weeks after surgery. The study also contained a control of patients with RA who were not on MTX Ann. Rheum. Dis. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and dental surgery Plaquenil Side Effects Common, Severe, Long Term -, Hydroxychloroquine Side Effects, Dosage, Uses, and More Tramadol and plaquenil Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Hold the immunomodulators for surgery? Maybe yes, maybe no.. Sulfasalazine Oral Route Precautions - Mayo Clinic. Aug 21, 2014 There are many risks of undergoing dental surgery while taking the drug Plaquenil. You can for example experience severe dizziness or drowsiness. The risk of osteonecrosis in irradiated fields, oral surgery should be performed before radiation treatment begins. Before Head and Neck Radiation Therapy • Conduct a pretreatment oral health examination and prophylaxis. • Schedule dental treatment in consultation with the radiation oncologist. Please help, my sister has sle, she has been under control with plaquenil for 15 years, she recently had surgery on both eyes, one was retinal detachment surg the other a minor lasik like procedure, ever since surgery she has been completely blind in both eyes, her retina has detached again and she is scheduled to have surgery again in 2 days.