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    Just a year after launching their generic version of Pfizer’s erectile dysfunction (ED) drug Viagra (sildenafil), Teva is taking on another blockbuster as they prepare to debut generic Cialis (tadalafil) in the US. Teva has secured fist-to-file status for generic Cialis which will grant them 180 days of market exclusivity before other generic pharmaceutical companies have a chance to get their own versions approved. “We’re proud to offer an affordable treatment option for the estimated 30 million men affected by ED, many of whom will also have symptomatic [benign prostatic hyperplasia] which is estimated to affect 15 million men in the United States,” said Hafrun Fridriksdottir, Teva’s Executive Vice President and Head of Global R&D. The company will be marketing four dosages (2.5 mg, 5 mg, 10 mg, 20 mg) in the country which will give patients the opportunity to access a generic substitution for their Cialis prescription. According to data from IQVIA, Cialis brought in close to 1.93 billion in US sales as of July of this year, offering Teva an opportunity to cash in on this lucrative market. According to an article published in Fierce Pharma, sales of Eli Lilly’s Cialis took a hit in 2017 when generic Viagra – including Teva’s version – began hitting pharmacy shelves. Teva’s generic Cialis will almost certainly further erode sales, with some analysts saying annual sales could drop as low as $55 million in the next four years. valacyclovir dosing The most common side effects include: headache, dyspepsia (i.e., pain or an uncomfortable feeling in the upper middle part of your stomach), back pain, myalgia (i.e., muscle pain), nasal congestion, flushing, and pain in limb. When Taken As Needed: The starting dose is usually 10 mg as needed prior to sexual activity but it depends on the individual. It has been shown to improve erectile function, compared to placebo, up to 36 hours post dose. When Taken Daily: The starting dose is 2.5 mg, taken at approximately the same time every day, without regard to timing of sexual activity. Based on effectiveness and tolerability, your physician may recommend an increase to 5 mg. Cialis has been shown to take effect in as little as 30 minutes. After single oral-dose administration, the maximum observed plasma concentration (Cmax) of tadalafil is achieved between 30 minutes and 6 hours (median time of 2 hours). Absolute bioavailability of tadalafil following oral dosing has not been determined.

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    Bioplastics Opportunities in Central Europe was fourth and also final conference organized within the PLASTi CE project and was held on September 23th and 24th in Slovenj Gradec. The conference which was joined with the Summer School of the Poly Region project was attended by more than 80 participants from 10 countries. PLASTi CE project and its outcomes were presented by project coordinator dr. Andrej Kržan and coordinators of two work packages. The main focus of the project is promotion of sustainable types of plastics and its use which was carried out using versatile dissemination routes form webpage, articles, brochures, books, social media and other. The international reach of project videos was also mentioned since this way project reached broader public and not only the Central European region. Stanislav Mertus, external member of the project, who managed to gather specialists on the field of biopolymers from different countries and motivated them to join the project as Focal Points for sustainable Plastics which is accessible on Three representatives of focal points presented the current situation with bioplastics in their countries (Egypt, Ukraine and Czech Republic). If you watch tv, listen to radio, or pay attention to the news, you are familiar with some of the available products that treat erectile dysfunction or impotency in men. Some brands you may recognize are viagra, cialis, and Levitra. Depending on your need or lifestyle, your doctor will determine which medication is the best fit for you. If you wish to have the most flexibility and control for your erection, to ask your doctor about Cialis. Some users refer to Cialis as “the weekend pill” because its effects allow you to achieve an erection any time you want for up to 36 hours following its intake! It may be taken daily when prescribed lower doses, as it also can treat benign prostatic hyperplasia (BPH) and high blood pressure in the lungs. These are just two of the many benefits of name-brand tadalafil.

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