Board-certified physicians medically review Drugwatch content to ensure its accuracy and quality. Drugwatch partners with Physicians’ Review Network Inc. PRN is a nationally recognized leader in providing independent medical reviews. Reviewer specialties include internal medicine, gastroenterology, oncology, orthopedic surgery and psychiatry. Effexor (venlafaxine) was the first antidepressant in the class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs). It is available in an extended-release formula to treat depression, and anxiety and panic disorders. It works by regulating levels of serotonin and norepinephrine in the brain. Board-certified physicians medically review Drugwatch content to ensure its accuracy and quality. duloxetine hcl dr caps Some doctors may prescribe venlafaxine off label for the treatment of diabetic neuropathy (in a similar manner to duloxetine) and migraine prophylaxis (in some people, however, venlafaxine can exacerbate or cause migraines). Studies have shown venlafaxine's effectiveness for these conditions, although agents that are marketed for this purpose (like pregabalin or duloxetine) are likely preferred. It has also been found to reduce the severity of 'hot flashes' in menopausal women and men on hormonal therapy for the treatment of prostate cancer. Due to its action on both the serotoninergic and adrenergic systems, venlafaxine is also used as a treatment to reduce episodes of cataplexy, a form of muscle weakness, in patients with the sleep disorder narcolepsy. A comparative meta-analysis of 21 major antidepressants found that venlafaxine, agomelatine, amitriptyline, escitalopram, mirtazapine, paroxetine, and vortioxetine were more effective than other antidepressants although the quality of many comparisons was assessed as low or very low. Venlafaxine is not recommended in patients hypersensitive to it, nor should it be taken by anyone who is allergic to the inactive ingredients, which include gelatin, cellulose, ethylcellulose, iron oxide, titanium dioxide and hypromellose. It should not be used in conjunction with a monoamine oxidase inhibitor (MAOI), as it can cause potentially fatal serotonin syndrome. 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When a person is struggling with bothersome Effexor side effects, or other problems related to this medication, they may consider Effexor alternatives help. We know other resolutions exist besides living a lifetime medicated on antidepressant drugs. Do you wish to see a loved one, or yourself start living live in a way you know is reachable? In many cases Effexor may not adequately treat symptoms or adverse Effexor side effects may occur, in cases such as these, Effexor alternatives therapy should be taken into consideration. If this antidepressant medication is not working like it should or if you are experiencing unwanted side effects, talk with your doctor about alternatives to Effexor. Depression is an extremely common problem in today’s world, even though there are treatments for depression such as antidepressant drugs, there are a lot of people seeking natural antidepressant alternatives for depression. 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