Treatment with olanzapine (like clozapine) may result in increased weight gain and increased glucose and cholesterol levels when compared to most other second-generation antipsychotic drugs used to treat schizophrenia. Agency for Healthcare Research and Quality concludes that olanzapine is not different from haloperidol in the treatment of positive symptoms and general psychopathology, or in overall assessment, but that it is superior for the treatment of negative and depressive symptoms. National Institute for Health and Care Excellence, the British Association for Psychopharmacology, and the World Federation of Societies for Biological Psychiatry suggest that there is little difference in effectiveness between antipsychotics in prevention of relapse, and recommend that the specific choice of antipsychotic be chosen based on a person's preference and the drug's side effect profile. In a 2013 comparison of 15 antipsychotic drugs in schizophrenia, olanzapine was ranked third in efficacy. It was 5% more effective than risperidone (4th), 24-27% more effective than haloperidol, quetiapine, and aripiprazole, and 33% less effective than clozapine (1st). A 2013 review of first episode schizophrenia concluded that olanzapine is superior to haloperidol in providing a lower discontinuation rate, and in short-term symptom reduction, response rate, negative symptoms, depression, cognitive function, discontinuation due to poor efficacy, and long-term relapse, but not in positive symptoms or on the Clinical Global Impressions score. In contrast, pooled second generation antipsychotics showed superiority to first generation antipsychotics only against the discontinuation, negative symptoms (with a much larger effect seen among industry- compared to government-sponsored studies), and cognition scores. Olanzapine caused less extrapyramidal side effects, less akathisia, but caused significantly more weight gain, serum cholesterol increase, and triglyceride increase than haloperidol. A 2011 review concluded that neither first- nor second generation antipsychotics produce clinically meaningful changes in Clinical Global Impression scores but found that olanzapine and amisulpride produce larger effects on the PANSS and BPRS batteries than five other second generation antipsychotics or pooled first generation antipsychotics. where to order levitra online Gruda Veterinary Hospital is a full service veterinary hospital located in Santa Fe, New Mexico. Our services include routine medical care, general surgery, dentistry, orthopedics, chiropractic, ultrasound, endoscopy and acupuncture for dogs, cats, and other small animals. Our goal is for you to enjoy the friendly, clean, and comfortable atmosphere while having the confidence that your pet is receiving the highest quality medical care and compassion. Our hospital is fully equipped with modern technology, allowing us to provide the highest level of care for your canine and feline family members. We know that you expect the very best for your pet, and we expect and require the same of ourselves. Most of all, we truly care about our patients and clients. Valtrex daily use Infants exposed to Inderal during pregnancy may have low birth weight, low blood. shortness of breath even with mild exertion, swelling, rapid weight gain;. fluconazole single dose Olanzapine, sold under the trade name Zyprexa among others, is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder. For schizophrenia, it can be used for both new onset disease and long term maintenance. It is taken by mouth or by injection into a muscle. Common side effect include weight gain, movement disorders, dizziness, feeling tired, constipation, and. Several cases have been reported to gain weight due to long-term treatment with propranolol. According to FDA, no case has been previously reported of sharp. Hi I have been taking this drug for over 6 months now. 40mg twice a day The cluster headaches that have plagued my life are now down to a bare minimum.....(not totally gone away) and manageable. I have gained about 1.5 stone in weight, particularly round my middle. My GP states this is NOT a recognised side effect and I simply must be eating more due to feeling better! As my eating habits have not changed at all, I find this very hard to accept. If I am to take this drug for the rest of my days, At this rate I will be enormous! PLEASE…can anyone help/confirm/reassure me that this is only a temporary side effect? Not like, you have 1-3 and you feel alone, like actually no friends. 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Weight gain is a known side effect of beta blockers, particularly older ones such as atenolol Tenormin and metoprolol Lopressor, Toprol-XL.