Welcome to HW....our lil family From what others have posted YES it can cause extreme fatigue or go the other way make you hyper...takes OR can take up to 4 to 6 weeks for this med to totally kick in and start to work .......... Are you on a benzo like Xanax or valium,ativan ect as well or just the zoloft???????? I am sure glad you found us here at HW and hoping that you do see the caring and support there is here ....... Go to Resources in yellow at side as well you can read on some back pages other threads about this or anything else you may want to know If not then start another thread ........you did here asking your questions.......... LYN **BTW** there are many self help techniques to learn and they do help you get theu this along with the meds such as Relaxation........ Cognitive behavioural Therapy ( free online one) and others I am sure ppl will post to help you lout Like I said this is a family and the support is fantastic as are the ppl.......... You have found a great place to gain advice on a lot of different issues/topics. I used to be on Zoloft and when I first started it, I was very tired, but eventually it did subside. Again, a warm welcome to the HW family and keep us posted on how things are going for you. Wen Co-Moderator Anxiety/Panic Disorders Evey little bit helps, please donate if you can! https:// Dx: Agoraphobia, Anxiety/Panic Disorders, Barrett's Esophagus, Bipolar Disorder, Depression, Fibromyalgia, I. S., Mitral Valve Prolapse, Narcolepsy, PTSD, Restless Leg Syndrome, Severe Acid Reflux, Sleep Apnea, Social Anxiety Rx: Abilify, Ambien CR, Ativan , Flexeril, Lamictal, Neurontin, Nexium, Requip, Ritalin ER, Valium Always bear in mind that your own resolution to succeed is more important than any other one thing. Abraham Lincoln It's been quite awhile since I've taken Zoloft but it took about 3-4 weeks before the extreme fatigue subsided. zithromax z-pak 250 mg I few days later, as if the depression was not bad enough, I began experiencing extreme fatigue and malaise. Prednisone and diarrhea Lbs 6'3 with fatigue that effects my productivity. hx adhd dx in early childhood, taken stimulants since then. I take 60mg xr a day in morning sometimes at 3pm, Lisinopril 40, Zoloft 150. zoloft samples Hi everyone. Glad you're here. Recently increased dose of Zoloft from 150 to 200. I few days later, as if the depression was not bad. I know fatigue is a common side effect of Zoloft, but wow. I sure hope this passes soon. I have been on Zoloft now for 7 days and I have slept. I am on Zoloft 50 mg since 6 months now, a month ago, I started to feel general fatigue and tiredness, now it is extreme, I feel tired after reading one page, and though, I keep laying down all day long, that affected my productivity and ability to study, totally. Regards and be well, pledge Thank you Pledge, I also believe that this can't be a side effect of Zoloft anymore, because I am on Zoloft for 6 months now and I didn't feel this before. I can just lay down for around 30 minutes, many times a day. Extreme fatique is a adverse effect to taking the drug. Your dose is low for Zoloft and you should not be feeling this tired. Since one month or more, it is worsening, now it is extreme fatigue and tiredness. I would love to see a doctor, but I stopped that, because I am now in a third world country, and I didn't find luck with the very few I came across here. Sorry to bother you, I will try best to find a good psychiatrist, as I mentioned it is not easy where I live. But I have a question, does an adverse reaction to Zoloft can develop later (coupe of months) of starting on the med? I don't know if it's the Zoloft or the Xanax. I know all my answers are going to be to go see my doctor but, I have recently been taken off of Celexa for Depression and put on Zoloft 9100mg) and Xanax (10mg) for Severe Anxiety and Depression. I split up my xanax into smaller doses more often instead of taking it in larger doses. (My doc said that was fine) I take 5mg about every 4 hours which he has prescribed for me 10mg twice a day. I think i'm younger than main target group of Cialis consumers, but i have a very hard work, i always had to listen about people's failures, about bad life et cetera. All that problems affected my sexual activity, my wife was not as happy as before with me. I tried Viagras - both generic and Pfizer's, and I may say Cialis that I ordered at your pharmacy is also a very good medicine. I'd recommend it to anybody with erection troubles. A found out about Viagra about three years ago and since that time taking these pills is as usual for me as brushing my teeth every day. It helps me lead the normal way of life and that's why I consider the drug to be worth of the money I pay for it. I am 36 and all my life I have been working hard to build a career that will let me be proud and independent. I'm sure that almost every woman felt herself completely frigid at least once. I lost sexual attraction to my husband, completely! But I came across one advertisement, it was like catching at a straw! But about two years ago I understood that it was high time for me to have a family. Not even a family as I do not believe in men, what I wanted is a baby or two to take care of and to give them attention and education. 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